The biliary tract includes the bile ducts, which carry bile from the liver to the small intestine, as well as the gallbladder. Biliary tract cancers (BTCs) refer to the cancers that arise from the cells that line the biliary system within or outside of the liver. Combination therapies targeting multiple pathways through various treatment modalities are increasingly being adopted for the treatment of BTCs, improving outcomes and extending survival.


The biliary tract cancers (BTCs) market is estimated to be valued at USD 0.822 billion in 2024 and is expected to reach USD 1.196 billion by 2031, growing at a compound annual growth rate (CAGR) of 5.5% from 2024 to 2031.

BTCs therapies include chemotherapy, radiation therapy, liver transplantation, and combination therapies. Combination therapies involving chemotherapy, targeted therapy, and immunotherapy agents are showing promising results with manageable safety profiles. This is leading to their increased adoption over monotherapies. The global Biliary Tract Cancers Market  is driven by the rising prevalence of biliary tract diseases as well as the growing adoption of new therapies and treatment innovations.





Key Takeaways

Key players: Key players operating in the BTCs market are F. Hoffmann-La Roche Ltd, Pfizer, Inc., Sanofi, Merck & Co., Inc., Novartis AG, and Bayer AG. These players are focusing on developing novel targeted therapies and immunotherapy drugs for improving patient outcomes.



Growing demand: The increasing incidence of biliary tract cancer and gallbladder cancer cases worldwide is driving the demand for improved diagnostic methods and effective treatment options. According to the American Cancer Society, approximately 8,980 new cases of biliary tract cancer will be diagnosed in the United States in 2022.



Global expansion: Major market players are expanding their global presence through acquisitions and collaborations. For instance, in 2021, Roche acquired Checkmate Pharmaceuticals to boost its immuno-oncology pipeline. Companies are also investing in research to develop novel combination therapies for hard-to-treat cancers.



Market Key Trends

Personalized medicine approaches are gaining traction in the BTCs market. Researchers are exploring ways to leverage genetic and molecular profiling to develop targeted therapies tailored to individual patient profiles and cancer subtypes. This trend is expected to transform treatment landscapes and improve clinical outcomes over the coming years.


Porter's Analysis

Threat of new entrants: Entry barriers in the BTC market are moderately high due to requiring large investments in R&D and clinical trials for drug development.

Bargaining power of buyers: Individual patients do not have significant bargaining power however collective bargaining of large healthcare providers and institutions can influence drug prices.

Bargaining power of suppliers: Major pharmaceutical companies developing drugs for BTC have some bargaining power due to patented drugs and scarce treatment alternatives currently available.

Threat of new substitutes: Potential for new drugs and treatment methods to emerge as substitute however R&D and approval timelines are significant.

Competitive rivalry: Competition expected to intensify with promising drug candidates in development however target patient segment remains focused for individual drug developers.



Geographical Regions

North America accounts for the largest share of the global BTC market, primarily due to the rising prevalence of gallbladder and bile duct cancers and the presence of well-established healthcare systems in the region. The availability of advanced diagnostic techniques and health reimbursement policies in the regional healthcare systems enables widespread diagnosis of BTCs, driving the regional market.



Asia Pacific is poised to witness the fastest growth over the forecast period owing to economic development in countries such as China and India, which has strengthened their healthcare systems. Apart from this, the large geriatric population base, unhealthy dietary habits, rising obesity, and increasing alcohol consumption are also fueling the incidence of BTCs in Asia Pacific. This results in high demand for advanced treatment solutions, thereby driving the regional market.

Get this Report in Japanese Language: 胆道がん市場

Get this Report in Korean Language: 담관암 시장

About Author:

Ravina Pandya, Content Writer, has a strong foothold in the market research industry. She specializes in writing well-researched articles from different industries, including food and beverages, information and technology, healthcare, chemical and materials, etc. (https://www.linkedin.com/in/ravina-pandya-1a3984191)